Osteoporosis is condition of decreased quantity and quality of bone resulting in fractures.
pathgenesis of osteoporosis involves the uncoupling of normal balance of bone formation and resorption. Bones are present structurally normal. In case of normal health the amount of formed equals the amount resorbed. In case of osteoporosis either too much bone is resorbed(high turn over) or too little is formed(low turn over).
- Risk factors
- Nutritional deficiency especially vitamin D.
- Post menopausal women.
- Cigarette smoking.
- Alcohol intake.
- Lack of exercise.
Malabsorption syndrome- due to lack of absorption of calcium can cause osteoporosis.
Chronic hyperthyroidism can result in increased bone turn over in osteoporosis.
Weight bearing is necessary for normal bone remodelling,obese persons have lesser chances of getting osteoporosis.
- Calcium supplementation is recommended-1500 mg elementary calcium/day.
- Vitamin D deficiency is to be treated.
- Risk factors of osteoporosis such as smoking alcoholism should be eliminated.